Journal article
The genetic mechanisms of primary angle closure glaucoma
Eye (London), Vol.29(10), pp.1251-1259
10/2015
DOI: 10.1038/eye.2015.124
PMCID: PMC4815686
PMID: 26206529
Abstract
Primary Angle Closure Glaucoma (PACG) is one of the most common types of glaucoma affecting over 15 million individuals worldwide. Family history and ethnicity are strongly associated with the development of the disease, suggesting that one or more genetic factors contribute to PACG. Although strictly heritable disease-causing mutations have not been identified, a number of recent association studies have pointed out genetic factors that appear to contribute to an individual's risk to develop PACG. In addition, genetic factors have been identified that modify PACG endophenotypes for example, axial length. Herein we review the current literature on this important topic.
Details
- Title: Subtitle
- The genetic mechanisms of primary angle closure glaucoma
- Creators
- D F Ahram - Department of Ophthalmology and Visual Sciences, The University of Iowa, Iowa City, IA, USAW L Alward - Department of Ophthalmology and Visual Sciences, The University of Iowa, Iowa City, IA, USAM H Kuehn - Department of Ophthalmology and Visual Sciences, The University of Iowa, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Eye (London), Vol.29(10), pp.1251-1259
- Publisher
- England
- DOI
- 10.1038/eye.2015.124
- PMID
- 26206529
- PMCID
- PMC4815686
- ISSN
- 1476-5454
- eISSN
- 1476-5454
- Language
- English
- Date published
- 10/2015
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9983979994802771
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