Logo image
The histopathologic effects of balloon dacryoplasty on the rabbit nasolacrimal duct
Journal article   Peer reviewed

The histopathologic effects of balloon dacryoplasty on the rabbit nasolacrimal duct

Scott M Goldstein, James A Katowitz and Nasreen A Syed
Journal of AAPOS, Vol.10(4), pp.333-335
08/2006
DOI: 10.1016/j.jaapos.2006.03.004
PMID: 16935233

View Online

Abstract

To examine the histopathologic effects of balloon dacryoplasty on the nasolacrimal duct of the rabbit. Sixteen nasolacrimal ducts of 8 infant white New Zealand rabbits were divided into 3 treatment groups: a control group, a 2 mm balloon dilation group, and a 3 mm balloon dilation group. The LacriCath balloon catheter (Quest, Medical, Allen, TX) was used for nasolacrimal duct dilation according to the manufacturer's recommended human protocol. The rabbits were euthanized at 1, 3, and 7 days after treatment and the nasolacrimal ducts were harvested for histological examination. There were no significant differences between treatment groups in the number of neutrophils in the lumen, epithelium, and stroma of the duct; the number of monocytes in the stroma of the duct; or in the number of red blood cells in the stroma of the duct. No differences were found in overall cellularity of any type in the nasolacrimal ducts of treated and untreated rabbits. Finally, no histopathologic signs of crush injury were evident. Balloon dacryoplasty does not induce significant inflammation or crush injury in the nasolacrimal duct of a rabbit model.
Animals, Newborn Nasolacrimal Duct - pathology Rabbits Animals Catheterization - methods Lacrimal Duct Obstruction - therapy Dacryocystorhinostomy - methods

Details

Metrics

Logo image