Journal article
The impact of keto-adaptation on exercise performance and the role of metabolic-regulating cytokines
The American journal of clinical nutrition, Vol.110(3), pp.562-573
09/01/2019
DOI: 10.1093/ajcn/nqz145
PMID: 31347659
Abstract
ABSTRACTThe ketogenic diet (KD) is a normocaloric diet composed of high-fat, low-carbohydrate, and adequate protein that induces fasting-like effects and results in the production of ketone bodies. Initially used widely for children with refractory epilepsy, the KD gained popularity due to its beneficial effects on weight loss, diabetes, and cancer. In recent years, there has been a resurgence in interest surrounding the KD and exercise performance. This review provides new insights into the adaptation period necessary for enhancement in skeletal muscle fat and ketone oxidation after sustained nutritional ketosis. In addition, this review highlights metabolically active growth factors and cytokines, which may function as important regulators of keto-adaptation in the setting of exercise and the KD.
Details
- Title: Subtitle
- The impact of keto-adaptation on exercise performance and the role of metabolic-regulating cytokines
- Creators
- Matthew Sherrier - Department of Physical Medicine and Rehabilitation, University of Pittsburgh Medical Center, Pittsburgh, PA, USAHongshuai Li - Musculoskeletal Growth and Regeneration Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
- Resource Type
- Journal article
- Publication Details
- The American journal of clinical nutrition, Vol.110(3), pp.562-573
- DOI
- 10.1093/ajcn/nqz145
- PMID
- 31347659
- NLM abbreviation
- Am J Clin Nutr
- ISSN
- 0002-9165
- eISSN
- 1938-3207
- Grant note
- name: Department of Orthopaedic Surgery
- Language
- English
- Date published
- 09/01/2019
- Academic Unit
- Orthopedics and Rehabilitation; Radiation Oncology
- Record Identifier
- 9984106516402771
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