Journal article
The impact of oculomotor functioning on neuropsychological performance in Huntington disease
Journal of clinical and experimental neuropsychology, Vol.38(2), pp.217-226
02/07/2016
DOI: 10.1080/13803395.2015.1101054
PMCID: PMC8091165
PMID: 26745770
Abstract
Huntington disease (HD) is a neurodegenerative condition with prominent motor (including oculomotor), cognitive, and psychiatric effects. While neuropsychological deficits are present in HD, motor impairments may impact performance on neuropsychological measures, especially those requiring a speeded response, as has been demonstrated in multiple sclerosis and schizophrenia. The current study is the first to explore associations between oculomotor functions and neuropsychological performance in HD. Participants with impaired oculomotor functioning performed worse than those with normal oculomotor functioning on cognitive tasks requiring oculomotor involvement, particularly on psychomotor speed tasks, controlling for covariates. Consideration of oculomotor dysfunction on neuropsychological performance is critical, particularly for populations with motor deficits.
Details
- Title: Subtitle
- The impact of oculomotor functioning on neuropsychological performance in Huntington disease
- Creators
- Janessa O Carvalho - Department of Psychology, Bridgewater State UniversityJeffrey D Long - Department of Biostatistics, College of Public Health, University of IowaHolly J Westervelt - Department of Neurology, Vanderbilt University Medical CenterMegan M Smith - Department of Neuropsychology, VA Maryland Healthcare SystemJared M Bruce - Department of Psychology, University of Missouri-Kansas CityJi-In Kim - Department of Psychiatry, Carver College of Medicine, University of IowaJames A Mills - Department of Psychiatry, Carver College of Medicine, University of IowaJane S Paulsen - Department of Psychology, University of IowaPREDICT-HD Investigators and Coordinators of the Huntington Study Group
- Contributors
- Hans J Johnson (Contributor) - University of Iowa, Electrical and Computer Engineering
- Resource Type
- Journal article
- Publication Details
- Journal of clinical and experimental neuropsychology, Vol.38(2), pp.217-226
- DOI
- 10.1080/13803395.2015.1101054
- PMID
- 26745770
- PMCID
- PMC8091165
- NLM abbreviation
- J Clin Exp Neuropsychol
- ISSN
- 1380-3395
- eISSN
- 1744-411X
- Publisher
- Taylor & Francis Group
- Grant note
- 5R01NS040068 / National Institute of Neurological Disorders and Stroke (10.13039/100000065) A2015; A6266 / CHDI Foundation (10.13039/100005725)
- Language
- English
- Date published
- 02/07/2016
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Electrical and Computer Engineering; Psychiatry; Psychological and Brain Sciences; Biostatistics; The Iowa Institute for Biomedical Imaging; The Iowa Initiative for Artificial Intelligence; Iowa Informatics Initiative
- Record Identifier
- 9984070695702771
Metrics
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