The impact of race and postoperative atrial fibrillation on operative mortality after elective coronary artery bypass grafting

Jimmy T Efird; Stephen W Davies; Wesley T O'Neal; Curtis A Anderson; Ethan J Anderson; Jason B O'Neal; T. Bruce Ferguson; W. Randolph Chitwood; Alan P Kypson

doi:10.1093/ejcts/ezt529

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The impact of race and postoperative atrial fibrillation on operative mortality after elective coronary artery bypass grafting

Journal article

Open access

Peer reviewed

The impact of race and postoperative atrial fibrillation on operative mortality after elective coronary artery bypass grafting

Jimmy T Efird, Stephen W Davies, Wesley T O'Neal, Curtis A Anderson, Ethan J Anderson, Jason B O'Neal, T. Bruce Ferguson, W. Randolph Chitwood and Alan P Kypson

European journal of cardio-thoracic surgery, Vol.45(2), pp.e20-e25

02/2014

DOI: 10.1093/ejcts/ezt529

PMID: 24288342

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Abstract

OBJECTIVE Black patients are less likely to develop postoperative atrial fibrillation (POAF) following coronary artery bypass grafting (CABG) than whites. However, the influence of race and POAF on operative mortality has not been examined. The objective of this study was to determine the influence of race and POAF on operative mortality after CABG. METHODS Patients undergoing elective CABG between 1992 and 2011 were included. Operative mortality was compared between patients with and those without new-onset POAF by race. Relative risk (RR) and 95% confidence intervals (CI) were computed using Poisson (robust variance estimates) and log-binomial regression models. RESULTS A total of 1215 (23%) patients developed POAF (white n = 1060; black n = 155) following CABG (N = 5387). Operative mortality differed by POAF status within race category (white POAF: adjusted RR = 1.4, 95% CI = 0.86-2.2; black POAF: adjusted RR = 5.0, 95% CI = 1.9-13; P interaction = 0.0016). Black POAF patients had a 2-fold increased risk of operative death compared with white POAF patients (P adjusted = 0.052). CONCLUSION POAF was observed to be a stronger predictor of operative mortality in black compared with white patients undergoing elective CABG.

CABG

Operative mortality

Survival

Race

Details

Title: Subtitle: The impact of race and postoperative atrial fibrillation on operative mortality after elective coronary artery bypass grafting
Creators: Jimmy T Efird - a Department of Cardiovascular Sciences, East Carolina Heart Institute, Brody School of Medicine, East Carolina University, Greenville, NC, USA
Stephen W Davies - c Department of General Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA
Wesley T O'Neal - d Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA
Curtis A Anderson - a Department of Cardiovascular Sciences, East Carolina Heart Institute, Brody School of Medicine, East Carolina University, Greenville, NC, USA
Ethan J Anderson - a Department of Cardiovascular Sciences, East Carolina Heart Institute, Brody School of Medicine, East Carolina University, Greenville, NC, USA
Jason B O'Neal - f Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
T. Bruce Ferguson - a Department of Cardiovascular Sciences, East Carolina Heart Institute, Brody School of Medicine, East Carolina University, Greenville, NC, USA
W. Randolph Chitwood - a Department of Cardiovascular Sciences, East Carolina Heart Institute, Brody School of Medicine, East Carolina University, Greenville, NC, USA
Alan P Kypson - a Department of Cardiovascular Sciences, East Carolina Heart Institute, Brody School of Medicine, East Carolina University, Greenville, NC, USA
Resource Type: Journal article
Publication Details: European journal of cardio-thoracic surgery, Vol.45(2), pp.e20-e25
DOI: 10.1093/ejcts/ezt529
PMID: 24288342
NLM abbreviation: Eur J Cardiothorac Surg
ISSN: 1010-7940
eISSN: 1873-734X
Publisher: Oxford University Press
Language: English
Date published: 02/2014
Academic Unit: Pharmaceutical Sciences and Experimental Therapeutics; Fraternal Order of Eagles Diabetes Research Center; Health, Sport, and Human Physiology
Record Identifier: 9984065689502771

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