Journal article
The implications of DSM-III personality disorders for patients with major depression
Journal of affective disorders, Vol.7(3), pp.309-318
1984
DOI: 10.1016/0165-0327(84)90052-1
PMID: 6241212
Abstract
We studied 78 inpatients with DSM-III major depression. Forty-one (53%) had a concurrent personality disorder (PD) according to a detailed structured interview for DSM-III personality disorders. The patients with depression plus PD differed from patients with depression alone on numerous measures. The PD patients had earlier onset; higher HRS scores; poorer social support; more life stressors; more frequent separation and divorce; more frequent nonserious suicide attempts, less frequent dexamethasone nonsuppression; poorer response to antidepressant medication; and higher risk for depression, alcoholism and antisocial personality among first-degree relatives. The PD subgroup shares many attributes with Winokur's subtype of depression spectrum disorder and Akiskal's character spectrum disorder. An attempt to identify a subgroup of personality disorders which might be an atypical affective disorder was inconclusive. However, patients in DSM-III cluster III were similar to the patients with no-PD on the dexamethasone suppression test, response to treatment, and familial risk for depression and antisocial personality.
Details
- Title: Subtitle
- The implications of DSM-III personality disorders for patients with major depression
- Creators
- Bruce PfohlDalene StanglMark Zimmerman
- Resource Type
- Journal article
- Publication Details
- Journal of affective disorders, Vol.7(3), pp.309-318
- DOI
- 10.1016/0165-0327(84)90052-1
- PMID
- 6241212
- NLM abbreviation
- J Affect Disord
- ISSN
- 0165-0327
- eISSN
- 1573-2517
- Publisher
- Elsevier B.V
- Language
- English
- Date published
- 1984
- Academic Unit
- Psychiatry
- Record Identifier
- 9984003985402771
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