Logo image
The influence of bio-behavioural factors on tumour biology: pathways and mechanisms
Journal article   Peer reviewed

The influence of bio-behavioural factors on tumour biology: pathways and mechanisms

Michael H Antoni, Susan K Lutgendorf, Steven W Cole, Firdaus S Dhabhar, Sandra E Sephton, Paige Green McDonald, Michael Stefanek and Anil K Sood
Nature reviews. Cancer, Vol.6(3), pp.240-248
03/2006
DOI: 10.1038/nrc1820
PMCID: PMC3146042
PMID: 16498446

View Online

Abstract

Epidemiological studies indicate that stress, chronic depression and lack of social support might serve as risk factors for cancer development and progression. Recent cellular and molecular studies have identified biological processes that could potentially mediate such effects. This review integrates clinical, cellular and molecular studies to provide a mechanistic understanding of the interface between biological and behavioural influences in cancer, and identifies novel behavioural or pharmacological interventions that might help improve cancer outcomes.
Animals Neoplasms - etiology Signal Transduction Humans Risk Factors Social Support Depression - complications Neoplasms - prevention & control Neoplasms - psychology Socioeconomic Factors Stress, Psychological - complications

Details

Logo image