Journal article
The link between stress disorders and autonomic dysfunction in muscular dystrophy
Frontiers in physiology, Vol.5, pp.25-25
2014
DOI: 10.3389/fphys.2014.00025
PMID: 24523698
Abstract
Muscular dystrophy is a progressive disease of muscle weakness, muscle atrophy and cardiac dysfunction. Patients afflicted with muscular dystrophy exhibit autonomic dysfunction along with cognitive impairment, severe depression, sadness, and anxiety. Although the psychological aspects of cardiovascular disorders and stress disorders are well known, the physiological mechanism underlying this relationship is not well understood, particularly in muscular dystrophy. Therefore, the goal of this perspective is to highlight the importance of autonomic dysfunction and psychological stress disorders in the pathogenesis of muscular dystrophy. This article will for the first time-(i) outline autonomic mechanisms that are common to both psychological stress and cardiovascular disorders in muscular dystrophy; (ii) propose therapies that would improve behavioral and autonomic functions in muscular dystrophy.
Details
- Title: Subtitle
- The link between stress disorders and autonomic dysfunction in muscular dystrophy
- Creators
- Rasna Sabharwal - Department of Internal Medicine, University of Iowa Carver College of Medicine Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Frontiers in physiology, Vol.5, pp.25-25
- DOI
- 10.3389/fphys.2014.00025
- PMID
- 24523698
- NLM abbreviation
- Front Physiol
- ISSN
- 1664-042X
- eISSN
- 1664-042X
- Publisher
- Switzerland
- Language
- English
- Date published
- 2014
- Academic Unit
- Iowa Neuroscience Institute; Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984065482502771
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