Journal article
The microscopic anatomy of the esophagus including the individual layers, specialized tissues, and unique components and their responses to injury
Annals of the New York Academy of Sciences, Vol.1434(1), pp.304-318
12/2018
DOI: 10.1111/nyas.13705
PMID: 29761508
Abstract
The esophagus, a straight tube that connects the pharynx to the stomach, has the complex architecture common to the rest of the gastrointestinal tract with special differences that relate to its function as a conduit of ingested substances. For instance, it has submucosal glands that are unique and have a specific protective function. It has a squamous lining that exists nowhere else in the gut except the anus and it has a different submucosal nerve plexus when compared to the stomach and intestines. All of the layers of the esophageal wall and the specialized structures including blood and lymphatic vessels and nerves have specific responses to injury. The esophagus also has unique features such as patches of gastric mucosa called inlet patches at the very proximal part and it has a special sphincter mechanism at the most distal aspect. This review covers the normal microscopic anatomy of the esophagus and the patterns of reaction to stress and injury of each layer and each special structure.
Details
- Title: Subtitle
- The microscopic anatomy of the esophagus including the individual layers, specialized tissues, and unique components and their responses to injury
- Creators
- Xuchen Zhang - Department of Pathology, Yale University, New Haven, ConnecticutDeepa Patil - Department of Pathology, Cleveland Clinic, Cleveland, OhioRobert D Odze - Department of Pathology, Harvard University, Boston, MassachusettsLei Zhao - Department of Pathology, Harvard University, Boston, MassachusettsMikhail Lisovsky - Department of Pathology, Dartmouth University, Lebanon, New HampshireMaha Guindi - Department of Pathology and Laboratory Medicine, Cedars-Sinai Hospital, Los Angeles, CaliforniaRobert Riddell - Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, OntarioAndrew Bellizzi - Department of Pathology, University of Iowa, Iowa City, IowaRhonda K Yantiss - Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New YorkIlke Nalbantoglu - Department of Pathology, Yale University, New Haven, ConnecticutHenry D Appelman - Department of Pathology, University of Michigan, Ann Arbor, Michigan
- Resource Type
- Journal article
- Publication Details
- Annals of the New York Academy of Sciences, Vol.1434(1), pp.304-318
- DOI
- 10.1111/nyas.13705
- PMID
- 29761508
- NLM abbreviation
- Ann N Y Acad Sci
- ISSN
- 0077-8923
- eISSN
- 1749-6632
- Publisher
- Wiley; United States
- Grant note
- P30 CA086862 / NCI NIH HHS
- Language
- English
- Date published
- 12/2018
- Academic Unit
- Pathology
- Record Identifier
- 9984047899502771
Metrics
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