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The middle meningeal artery as an alternative route for intra-arterial chemotherapy
Journal article   Open access   Peer reviewed

The middle meningeal artery as an alternative route for intra-arterial chemotherapy

Mario Zanaty, Nohra Chalouhi, Carol L. Shields, Stavropoula Tjoumakaris, Robert H. Rosenwasser and Pascal Jabbour
Interdisciplinary neurosurgery : Advanced techniques and case management, Vol.2(2), pp.76-78
06/01/2015
DOI: 10.1016/j.inat.2015.02.003
url
https://doi.org/10.1016/j.inat.2015.02.003View
Published (Version of record) Open Access

Abstract

Retinoblastoma is a deadly eye cancer in children, leading to death in 50%-70% of children in undeveloped nations. Unfortunately, this aggressive tumor is the most common intraocular malignancy worldwide. For the last 2 decades, intravenous (IV) chemotherapy has been the mainstay of treatment for retinoblastomas. This route has provided improved control in retinoblastoma, with sparing of the eye and vision in some cases. More recently, intra-arterial chemotherapy (IAC) has become the first line treatment for advanced and refractory retinoblastoma in many centers worldwide. The advances in treatment along with early tumor detection are responsible for the favorable prognosis found in developed nations. IAC classically uses the ophthalmic artery (OA) in attempt to deliver the maximal dose of chemotherapy while minimizing systemic complications. However, direct catheterization of the ophthalmic artery (OA) is not always possible. The purpose of this article is to describe a case where the OA has been thrombosed and an alternative access route using the middle meningeal artery (MMA) was used. (C) 2015 The Authors. Published by Elsevier B.V.
 Clinical Neurology Life Sciences & Biomedicine Neurosciences & Neurology Science & Technology

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