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The molecular genetics of Bardet–Biedl syndrome
Journal article   Peer reviewed

The molecular genetics of Bardet–Biedl syndrome

Val C Sheffield, Darryl Nishimura and Edwin M Stone
Current Opinion in Genetics & Development, Vol.11(3), pp.317-321
2001
DOI: 10.1016/S0959-437X(00)00196-9
PMID: 11377969

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Abstract

Bardet–Biedl syndrome (BBS) has been shown to be a genetically heterogeneous disorder involving genes mapping to at least six known loci. One BBS gene ( MKKS) has been identified and the form of the disorder caused by this gene is allelic to McKusick–Kaufman syndrome. MKKS codes for a putative chaperonin, suggesting that other BBS genes may also code for components of chaperone complexes or be substrates of chaperone function.
retinopathy chaperonin McKusick-Kaufman syndrome Bardet-Biedl syndrome diabetes hypertension obesity polydactyly

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