Journal article
The neuronal response to electrical constant-amplitude pulse train stimulation: additive Gaussian noise
Hearing research, Vol.149(1-2), pp.129-137
11/01/2000
DOI: 10.1016/S0378-5955(00)00173-8
PMID: 11033252
Abstract
Experimental results from humans and animals show that electrically evoked compound action potential (EAP) responses to constant-amplitude pulse train stimulation can demonstrate an alternating pattern, due to the combined effects of highly synchronized responses to electrical stimulation and refractory effects (Wilson et al., 1994). One way to improve signal representation is to reduce the level of across-fiber synchrony and hence, the level of the amplitude alternation. To accomplish this goal, we have examined EAP responses in the presence of Gaussian noise added to the pulse train stimulus. Addition of Gaussian noise at a level approximately -30 dB relative to EAP threshold to the pulse trains decreased the amount of alternation, indicating that stochastic resonance may be induced in the auditory nerve. The use of some type of conditioning stimulus such as Gaussian noise may provide a more 'normal' neural response pattern.
Details
- Title: Subtitle
- The neuronal response to electrical constant-amplitude pulse train stimulation: additive Gaussian noise
- Creators
- A J Matsuoka - University of IowaP J Abbas - University of IowaJ T Rubinstein - University of IowaC A Miller - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Hearing research, Vol.149(1-2), pp.129-137
- DOI
- 10.1016/S0378-5955(00)00173-8
- PMID
- 11033252
- ISSN
- 0378-5955
- eISSN
- 1878-5891
- Grant note
- DC62111 / NIDCD NIH HHS
- Language
- English
- Date published
- 11/01/2000
- Academic Unit
- Otolaryngology
- Record Identifier
- 9984383288402771
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