The palpable breast nodule. A cost-effectiveness analysis of alternate diagnostic approaches

Lester J Layfield; Elizabeth A Chrischilles; Michael B Cohen; Kent Bottles

doi:10.1002/1097-0142(19930901)72:5<1642::aid-cncr2820720525>3.0.co;2-8

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The palpable breast nodule. A cost-effectiveness analysis of alternate diagnostic approaches

Journal article

Open access

Peer reviewed

The palpable breast nodule. A cost-effectiveness analysis of alternate diagnostic approaches

Lester J Layfield, Elizabeth A Chrischilles, Michael B Cohen and Kent Bottles

Cancer, Vol.72(5), pp.1642-1651

09/01/1993

DOI: 10.1002/1097-0142(19930901)72:5<1642::aid-cncr2820720525>3.0.co;2-8

PMID: 8348496

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https://doi.org/10.1002/1097-0142(19930901)72:5<1642::aid-cncr2820720525>3.0.co;2-8View

Published (Version of record) Open Access

Abstract

Traditionally, open biopsy has been considered the optimal procedure for the diagnosis of breast nodules. Fine-needle aspiration biopsy (FNAB) has been proposed as an alternate method for the diagnosis of many palpable breast lesions. The authors compared the diagnostic utility of open biopsy and FNAB using decision tree and cost-effectiveness analyses. When compared with two-step excisional biopsy, FNAB achieved a savings of over $700 at the cost of 0.1% decrease in 10-year overall survival. These data indicate FNAB to be a reasonable alternative to open biopsy for the diagnosis of palpable breast lesions in many patients.

Biopsy - methods

Breast Neoplasms - surgery

Predictive Value of Tests

Breast Neoplasms - economics

Frozen Sections - economics

Outcome Assessment (Health Care)

Humans

Middle Aged

Life Expectancy

Aged, 80 and over

Adult

Female

Intraoperative Care - economics

Biopsy - economics

Terminal Care - economics

Ambulatory Surgical Procedures - economics

Costs and Cost Analysis

Decision Support Techniques

Survival Rate

Mammography

Biopsy, Needle - economics

Biopsy, Needle - methods

Cost-Benefit Analysis

Aged

Breast Neoplasms - diagnosis

Decision Trees

Neoplasm Staging

Details

Title: Subtitle: The palpable breast nodule. A cost-effectiveness analysis of alternate diagnostic approaches
Creators: Lester J Layfield - Department of Pathology, Duke University Medical Center, Durham, NC 27705
Elizabeth A Chrischilles
Michael B Cohen
Kent Bottles
Resource Type: Journal article
Publication Details: Cancer, Vol.72(5), pp.1642-1651
Publisher: United States
DOI: 10.1002/1097-0142(19930901)72:5<1642::aid-cncr2820720525>3.0.co;2-8
PMID: 8348496
ISSN: 0008-543X
eISSN: 1097-0142
Language: English
Date published: 09/01/1993
Academic Unit: Pharmacy; Epidemiology; Pathology
Record Identifier: 9983996089402771

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