Journal article
The pathways of interoceptive awareness
Nature neuroscience, Vol.12(12), pp.1494-1496
11/01/2009
DOI: 10.1038/nn.2411
PMCID: PMC2787640
PMID: 19881506
Abstract
A network of cortical brain regions, including the insula and anterior cingulate cortex (ACC), has been proposed as the critical and sole substrate for interoceptive awareness. Combining lesion and pharmacological approaches in humans, we found that the insula and ACC were not critical for awareness of heartbeat sensations. Instead, this awareness was mediated by both somatosensory afferents from the skin and a network that included the insula and ACC. Together, these pathways enable the core human experience of the cardiovascular state of the body.
Details
- Title: Subtitle
- The pathways of interoceptive awareness
- Creators
- Sahib S Khalsa - Department of Neurology and Neuroscience Program, University of Iowa Medical Scientist Training Program, University of IowaDavid Rudrauf - Department of Neurology and Neuroscience Program, University of IowaJustin S Feinstein - University of Iowa, NeurologyDaniel Tranel - University of Iowa, Neurology
- Resource Type
- Journal article
- Publication Details
- Nature neuroscience, Vol.12(12), pp.1494-1496
- DOI
- 10.1038/nn.2411
- PMID
- 19881506
- PMCID
- PMC2787640
- NLM abbreviation
- Nat Neurosci
- ISSN
- 1097-6256
- eISSN
- 1546-1726
- Publisher
- Springer Science and Business Media LLC
- Language
- English
- Date published
- 11/01/2009
- Academic Unit
- Neurology; Psychological and Brain Sciences; Iowa Neuroscience Institute
- Record Identifier
- 9984002581902771
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