Journal article
The preussomerins: novel antifungal metabolites from the coprophilous fungus Preussia isomera Cain
Journal of organic chemistry, Vol.56(14), pp.4355-4360
07/01/1991
DOI: 10.1021/jo00014a007
Abstract
Preussomerins A-F (1-6), a series of new aromatic bis-ketals with antifungal and antibacterial activities, have been isolated from the coprophilous fungus Preussia isomera (CBS 415.82). Preussomerins A-F were obtained from ethyl acetate extracts of liquid cultures of P. isomera by silica gel chromatography and reversed-phase HPLC. The structures of preussomerins B-F (2-6) were proposed on the basis of extensive NMR experiments and by comparison with the data for preussomerin A (1), whose structure was confirmed by single-crystal X-ray diffraction analysis. The isolation process was guided by in vitro bioassays for antifungal antagonism toward other coprophilous fungi. © 1991, American Chemical Society. All rights reserved.
Details
- Title: Subtitle
- The preussomerins: novel antifungal metabolites from the coprophilous fungus Preussia isomera Cain
- Creators
- Holly A WeberJames B Gloer
- Resource Type
- Journal article
- Publication Details
- Journal of organic chemistry, Vol.56(14), pp.4355-4360
- Publisher
- American Chemical Society
- DOI
- 10.1021/jo00014a007
- ISSN
- 0022-3263
- eISSN
- 1520-6904
- Language
- English
- Date published
- 07/01/1991
- Academic Unit
- Chemistry
- Record Identifier
- 9984216571802771
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