Journal article
The questionnaire for urinary incontinence diagnosis (QUID): validity and responsiveness to change in women undergoing non-surgical therapies for treatment of stress predominant urinary incontinence
Neurourology and urodynamics, Vol.29(5), pp.727-734
0
06/01/2010
DOI: 10.1002/nau.20818
PMID: 19787711
Abstract
<p>AIMS: The Questionnaire for Urinary Incontinence Diagnosis (QUID), a 6-item urinary incontinence (UI) symptom questionnaire, was developed and validated to distinguish stress and urge UI. This study's objective was to evaluate QUID validity and responsiveness when used as a clinical trial outcome measure. METHODS: Participants enrolled in a multi-center trial of non-surgical therapy (continence pessary, pelvic floor muscle training or combined) for stress-predominant UI and completed baseline and 3-month diaries, the Urinary Distress Inventory (UDI) and QUID. Data from all treatment groups were pooled. QUID internal consistency (Cronbach's alpha) and convergent/discriminant validity (Pearson correlations) were evaluated. Responsiveness to change was assessed with 3-month score outcomes and distribution-based measurements. RESULTS: Four hundred forty-four women (mean age 50) were enrolled with stress (N = 200) and mixed (N = 244) UI; 344 had 3-month data. Baseline QUID Stress and Urge scores (both scaled 0-15, larger values indicating worse UI) were 8.4 +/- 3.2 and 4.5 +/- 3.3, respectively. Internal consistency of QUID Total, Stress, and Urge scores was 0.75, 0.64 and 0.87, respectively. QUID Stress scores correlated moderately with UDI-Stress scores (r = 0.68, P < 0.0001) and diary stress UI episodes (r = 0.41, P < 0.0001). QUID Urge scores correlated moderately with UDI-Irritative scores (r = 0.68, P < 0.0001) and diary urge UI episodes (r = 0.45, P < 0.0001). Three-month QUID Stress and Urge scores improved (4.1 +/- 3.4 and 2.2 +/- 2.7, both P < 0.0001). QUID Stress score effect size (1.3) and standardized response mean (1.2) suggested a large change after therapy. CONCLUSION: The QUID has acceptable psychometric characteristics and may be used as a UI outcome measure in clinical trials.</p>
Details
- Title: Subtitle
- The questionnaire for urinary incontinence diagnosis (QUID): validity and responsiveness to change in women undergoing non-surgical therapies for treatment of stress predominant urinary incontinence
- Creators
- Catherine S. Bradley - University of IowaDavid D. Rahn - University of Texas Southwestern Medical CenterIngrid E. Nygaard - University of UtahMatthew D. Barber - Cleveland ClinicCharles W. Nager - University of California - San DiegoKimberly S. Kenton - Loyola University ChicagoNazema Y. Siddiqui - Duke UniversityRobert B. Abel - The University Of MichiganCathie Spino - The University Of MichiganHolly E. Richter - University of Alabama, BirminghamPelvic Floor Disorders Network
- Resource Type
- Journal article
- Publication Details
- Neurourology and urodynamics, Vol.29(5), pp.727-734
- Event
- 0
- DOI
- 10.1002/nau.20818
- PMID
- 19787711
- NLM abbreviation
- Neurourol Urodyn
- ISSN
- 1520-6777
- Grant note
- name: Eunice Kennedy Shriver National Institute of Child Health and Human Development, award: K23 HD047654, U01 HD41249, U10 HD41268, U10 HD41248, U10 HD41250, U10 HD41261, U10 HD41263, U10 HD41269, U10 HD41267; DOI: 10.13039/100000124, name: Office of Research on Women's Health; DOI: 10.13039/100000062, name: National Institute of Diabetes and Digestive and Kidney Disease
- Comment
Supported by grants from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (K23 HD047654, U01 HD41249, U10 HD41268, U10 HD41248, U10 HD41250, U10 HD41261, U10 HD41263, U10 HD41269, and U10 HD41267), the Office of Research on Women’s Health, and the National Institute of Diabetes and Digestive and Kidney Disease.
- Language
- English
- Date published
- 06/01/2010
- Academic Unit
- Epidemiology; Obstetrics and Gynecology; Urology
- Record Identifier
- 9983557794502771
Metrics
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