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The recent origins of introns
Journal article   Peer reviewed

The recent origins of introns

Jeffrey D Palmer and John M Logsdon
Current opinion in genetics & development, Vol.1(4), pp.470-477
1991
DOI: 10.1016/S0959-437X(05)80194-7
PMID: 1822279

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Abstract

Accumulating evidence that introns are highly restricted in their phylogenetic distribution strongly supports the view that introns were inserted late in eukaryotic evolution into preformed genes and, hence, that exon-shuffling played no role in the assembly of primordial genes. Potential mechanisms of intron insertion and the possible evolution of nuclear introns and their splicing machinery from self-splicing group II introns are also discussed.
MDH SLRNAs snRNAs AFP AAT GAPDH

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