Journal article
The recent origins of spliceosomal introns revisited
Current opinion in genetics & development, Vol.8(6), pp.637-648
1998
DOI: 10.1016/S0959-437X(98)80031-2
PMID: 9914210
Abstract
Does the intron/exon structure of eukaryotic genes belie their ancient assembly by exon-shuffling or have introns been inserted into preformed genes during eukaryotic evolution? These are the central questions in the ongoing ‘introns-early’ versus ‘introns-late’ controversy. The phylogenetic distribution of spliceosomal introns continues to strongly favor the intronslate theory. The introns-early theory, however, has claimed support from intron phase and protein structure correlations.
Details
- Title: Subtitle
- The recent origins of spliceosomal introns revisited
- Creators
- John M Logsdon - Department of Biochemistry, Dalhousie University, Halifax, Nova Scotia, B3H 4H7 Canada
- Resource Type
- Journal article
- Publication Details
- Current opinion in genetics & development, Vol.8(6), pp.637-648
- DOI
- 10.1016/S0959-437X(98)80031-2
- PMID
- 9914210
- NLM abbreviation
- Curr Opin Genet Dev
- ISSN
- 0959-437X
- eISSN
- 1879-0380
- Publisher
- Elsevier Ltd
- Language
- English
- Date published
- 1998
- Academic Unit
- Biology
- Record Identifier
- 9984217412402771
Metrics
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