Journal article
The regulation of Streptococcus mutans glucan-binding protein A expression
FEMS microbiology letters, Vol.154(2), pp.289-292
1997
DOI: 10.1016/S0378-1097(97)00344-3
PMID: 9311127
Abstract
The
S. mutans GBP-A is hypothesized to be constitutively expressed and to contribute to the sucrose-dependent colonization of
S. mutans. To investigate GBP-A expression, a reporter gene encoding chloramphenicol acetyltransferase (
CAT) was placed downstream of the
gbpA promoter and CAT activity was measured under conditions that would be associated with the sucrose-dependent colonization of
S. mutans. Expression of GBP-A was optimal under anaerobiosis and neutral pH conditions, and correlated with optimal growth. The addition of sucrose to the growth medium did not elevate the expression of GBP-A.
Details
- Title: Subtitle
- The regulation of Streptococcus mutans glucan-binding protein A expression
- Creators
- Jeffrey A BanasHeather C PotvinRenita N Singh
- Resource Type
- Journal article
- Publication Details
- FEMS microbiology letters, Vol.154(2), pp.289-292
- DOI
- 10.1016/S0378-1097(97)00344-3
- PMID
- 9311127
- NLM abbreviation
- FEMS Microbiol Lett
- ISSN
- 0378-1097
- eISSN
- 1574-6968
- Publisher
- Elsevier B.V
- Language
- English
- Date published
- 1997
- Academic Unit
- Pediatric Dentistry; Dental Research
- Record Identifier
- 9984065987802771
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