The relationship between age and post-dexamethasone cortisol: A test of three hypotheses

Dalene Stangl; Bruce Pfohl; Mark Zimmerman; William Coryell; Caryn Corenthal

doi:10.1016/0165-0327(86)90069-8

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The relationship between age and post-dexamethasone cortisol: A test of three hypotheses

Journal article

Peer reviewed

The relationship between age and post-dexamethasone cortisol: A test of three hypotheses

Dalene Stangl, Bruce Pfohl, Mark Zimmerman, William Coryell and Caryn Corenthal

Journal of affective disorders, Vol.11(3), pp.185-197

1986

DOI: 10.1016/0165-0327(86)90069-8

PMID: 2951406

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Abstract

Previous studies report that DST nonsuppressors are older than normal suppressors. Data are presented on 188 primary unipolar major depressive inpatients and 35 healthy controls. In males, age appeared to correlate positively with post-dexamethasone cortisols in depressed patients and normal controls, although mean levels were higher in depressives. Female controls showed no consistent relationship between age and post-dexamethasone cortisol. A positive relationship did exist for depressed women. However, the association disappeared when age-of-onset was entered into the model, suggesting that in females early onset may identify a subtype of depression with normal DST suppression.

Dexamethasone suppression test

Cortisol

Age

Details

Title: Subtitle: The relationship between age and post-dexamethasone cortisol: A test of three hypotheses
Creators: Dalene Stangl
Bruce Pfohl
Mark Zimmerman
William Coryell
Caryn Corenthal
Resource Type: Journal article
Publication Details: Journal of affective disorders, Vol.11(3), pp.185-197
DOI: 10.1016/0165-0327(86)90069-8
PMID: 2951406
NLM abbreviation: J Affect Disord
ISSN: 0165-0327
eISSN: 1573-2517
Publisher: Elsevier B.V
Language: English
Date published: 1986
Academic Unit: Psychiatry
Record Identifier: 9984003909002771

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