Journal article
The relationship between respiratory syncytial virus and asthma
Veterinary pathology, Vol.52(1), pp.97-106
01/2015
DOI: 10.1177/0300985814520639
PMID: 24513802
Abstract
Asthma is a chronic inflammatory disease of the lung that is a leading cause of morbidity and mortality in children worldwide. Most infants who experience wheezing episodes also exhibit evidence of an ongoing respiratory viral infection. Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection in children and is a common cause of wheezing in infants and young children. In the past several decades, a number of studies have demonstrated a relationship between infants with severe RSV infections and the subsequent development of asthma later during childhood. This review provides an overview of data that suggests a severe RSV infection early in childhood is linked to development of asthma later in life. In addition, the current and potential future use of various animal models to gain additional insight into the relationship between RSV and asthma is discussed.
Details
- Title: Subtitle
- The relationship between respiratory syncytial virus and asthma
- Creators
- C J Knudson - Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, IA, USAS M Varga - Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, IA, USA Department of Microbiology, University of Iowa, Iowa City, IA, USA Department of Pathology, University of Iowa, Iowa City, IA, USA steven-varga@uiowa.edu
- Resource Type
- Journal article
- Publication Details
- Veterinary pathology, Vol.52(1), pp.97-106
- DOI
- 10.1177/0300985814520639
- PMID
- 24513802
- ISSN
- 0300-9858
- eISSN
- 1544-2217
- Grant note
- T32 AI007485 / NIAID NIH HHS
- Language
- English
- Date published
- 01/2015
- Academic Unit
- Graduate College Admin and Gen; Microbiology and Immunology; Pathology
- Record Identifier
- 9984083890602771
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