Journal article
The relationship of three-dimensional joint space width on weight-bearing CT with pain and physical function
Journal of orthopaedic research, Vol.38(6), pp.1333-1339
06/01/2020
DOI: 10.1002/jor.24566
PMCID: PMC8016550
PMID: 31840831
Abstract
Limitations of plain radiographs may contribute to poor sensitivity in the detection of knee osteoarthritis and poor correlation with pain and physical function. Three-dimensional (3D) joint space width (JSW), measured from weight-bearing computed tomography (CT) images, may yield a more accurate correlation with patients' symptoms. We assessed the cross-sectional association between 3D JSW and self-reported pain and physical function. Five hundred twenty eight knees (57% women) were analyzed from Multicenter Osteoarthritis Study participants. An upright weight-bearing CT scanner was used to acquire bilateral, weight-bearing, fixed-flexion images of the knees. A 3D dataset was reconstructed from cone beam projections and JSW was calculated across the joint surface. The percentages of the apposed medial tibiofemoral joint surface with JSW less than 2.0 and 2.5 mm, respectively, were calculated. Pain and physical function were measured using Western Ontario and McMaster Universities Osteoarthritis Index. Participants who reported greater pain severity tended to have a greater joint area with JSW less than 2.0 mm (P = .07 for the highest vs the lowest tertile). Participants who reported greater functional limitations had a greater joint area with JSW less than 2.0 mm (P = .02 for the highest vs the lowest tertile). There appears to be an association between the medial tibiofemoral area with JSW less than 2.0 mm and pain and physical function.
Details
- Title: Subtitle
- The relationship of three-dimensional joint space width on weight-bearing CT with pain and physical function
- Creators
- Mayank D. Kothari - Univ Kansas, Dept Rehabil Med, 3901 Rainbow Blvd,Mailstop 1046, Kansas City, KS 66160 USAKaitlin G. Rabe - The University of Texas at DallasDonald D. Anderson - University of IowaMichael C. Nevitt - University of California, San FranciscoJohn A. Lynch - University of California, San FranciscoHayden Franz - Univ Kansas, Dept Rehabil Med, 3901 Rainbow Blvd,Mailstop 1046, Kansas City, KS 66160 USANeil A. Segal - The University of Kansas, Kansas City, 3901 Rainbow Boulevard, Mailstop 1046; KUMC Department of Rehabilitation Medicine, Kansas City, KS, 66160.Multicenter Osteoarthritis Study Group
- Resource Type
- Journal article
- Publication Details
- Journal of orthopaedic research, Vol.38(6), pp.1333-1339
- DOI
- 10.1002/jor.24566
- PMID
- 31840831
- PMCID
- PMC8016550
- NLM abbreviation
- J Orthop Res
- ISSN
- 0736-0266
- eISSN
- 1554-527X
- Publisher
- Wiley
- Number of pages
- 7
- Grant note
- R01 AR071648 / National Institute of Arthritis and Musculoskeletal and Skin Diseases; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Arthritis & Musculoskeletal & Skin Diseases (NIAMS) U01AG018832 / NATIONAL INSTITUTE ON AGING; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA) R01AR071648 / NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Arthritis & Musculoskeletal & Skin Diseases (NIAMS) U01AG18820; U01AG18832; U01AG18947; U01AG19069 / National Institute on Aging; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA)
- Language
- English
- Date published
- 06/01/2020
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Epidemiology; Orthopedics and Rehabilitation; Industrial and Systems Engineering
- Record Identifier
- 9984304687502771
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