The role of anticoagulation in the management of pediatric temporal bone septic thrombophlebitis

Joseph P Roche; Marlan R Hansen

doi:10.1002/lary.25755

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The role of anticoagulation in the management of pediatric temporal bone septic thrombophlebitis

Journal article

Open access

Peer reviewed

The role of anticoagulation in the management of pediatric temporal bone septic thrombophlebitis

Joseph P Roche and Marlan R Hansen

The Laryngoscope, Vol.126(5), pp.1027-1028

05/2016

DOI: 10.1002/lary.25755

PMID: 26666669

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https://doi.org/10.1002/lary.25755View

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Abstract

BACKGROUND Lateral dural venous sinus thrombosis (LST) represents a serious complication of acute or chronic otitis media. It is thought to develop from the progression of inflammation and granulation tissue formation in the perisinus bone to infection of the sinus wall proper, with incitement of mural thrombosis. Treatment of LST typically includes the administration of broad‐spectrum parenteral antibiotics and surgical decompression of the middle ear and/or mastoid. The safety and efficacy of anticoagulation in the management of LST remains controversial. Proponents of anticoagulation argue that this treatment enhances the resolution of symptoms, helps reestablish sinus patency, and reduces intracranial pressure in cases of otitic hydrocephalus.1, 2 However, others argue that anticoagulation carries serious risks without definitive benefit.3 This best practice review addresses three interrelated issues of anticoagulation for LST: 1) is anticoagulation safe in patients with LST; 2) does anticoagulation impact the likelihood of dural venous sinus recanalization; and 3) does anticoagulation impact the likelihood of long‐term symptom resolution.

Temporal Bone

Humans

Sinus Thrombosis, Intracranial - etiology

Anticoagulants - therapeutic use

Otitis Media - complications

Thrombophlebitis - drug therapy

Sinus Thrombosis, Intracranial - drug therapy

Anticoagulants - adverse effects

Thrombophlebitis - etiology

Child

Details

Title: Subtitle: The role of anticoagulation in the management of pediatric temporal bone septic thrombophlebitis
Creators: Joseph P Roche - Department of Otolaryngology-Head and Neck Surgery, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, U.S.A
Marlan R Hansen - Department of Neurosurgery, The University of Iowa Carver College of Medicine, Iowa City, Iowa, U.S.A
Resource Type: Journal article
Publication Details: The Laryngoscope, Vol.126(5), pp.1027-1028
DOI: 10.1002/lary.25755
PMID: 26666669
NLM abbreviation: Laryngoscope
ISSN: 0023-852X
eISSN: 1531-4995
Publisher: United States
Language: English
Date published: 05/2016
Academic Unit: Molecular Physiology and Biophysics; Neurosurgery; Otolaryngology
Record Identifier: 9984006344302771

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