Journal article
The role of radiotherapy in the management of progressive glioblastoma: A systematic review and evidence-based clinical practice guideline
Journal of neuro-oncology, Vol.118(3), pp.489-499
07/2014
DOI: 10.1007/s11060-013-1337-6
PMID: 24728785
Abstract
Can re-irradiation (by using conventional radiotherapy, fractionated radiosurgery, or single fraction radiosurgery) be used in patients with progressive glioblastoma multiforme after the first adjuvant combined multimodality treatment with radiation and chemotherapy?These recommendations apply to adult patients with progressive glioblastoma after first line combined multimodality treatment with chemotherapy and radiation.When the target tumor is amenable for additional radiation, re-irradiation is recommended as it provides improved local tumor control, as measured by best imaging response. Such re-irradiation can take the form of conventional fractionation radiotherapy, fractionated radiosurgery, or single fraction radiosurgery.Re-irradiation is recommended in order to maintain or improve a patient’s neurological status and quality of life prior to any further tumor progression.
Details
- Title: Subtitle
- The role of radiotherapy in the management of progressive glioblastoma: A systematic review and evidence-based clinical practice guideline
- Creators
- Samuel Ryu - Department of Radiation Oncology Stony Brook University School of Medicine Stony Brook NY USAJohn Buatti - Department of Radiation Oncology University of Iowa Hospitals & Clinics Iowa City IA USAAnn Morris - Department of Radiation Oncology University of Iowa Hospitals & Clinics Iowa City IA USASteven Kalkanis - Department of Neurosurgery Henry Ford Health System Detroit MI USATimothy Ryken - Department of Neurosurgery Iowa Spine and Brain Institute and University of Iowa Waterloo, Iowa City IA USAJeffrey Olson - Department of Neurosurgery Emory University School of Medicine Atlanta GA USA
- Resource Type
- Journal article
- Publication Details
- Journal of neuro-oncology, Vol.118(3), pp.489-499
- Publisher
- Springer US; Boston
- DOI
- 10.1007/s11060-013-1337-6
- PMID
- 24728785
- ISSN
- 0167-594X
- eISSN
- 1573-7373
- Language
- English
- Date published
- 07/2014
- Academic Unit
- Radiation Oncology; Neurosurgery; Otolaryngology
- Record Identifier
- 9984040316902771
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