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The round trip model for severe herpes zoster caused by live attenuated varicella vaccine virus
Journal article   Open access   Peer reviewed

The round trip model for severe herpes zoster caused by live attenuated varicella vaccine virus

Charles Grose and Lynn W. Enquist
Journal of medical virology, Vol.92(8), pp.938-940
08/2020
DOI: 10.1002/jmv.25664
PMCID: PMC7354881
PMID: 31943220
url
https://doi.org/10.1002/jmv.25664View
Published (Version of record) Open Access

Abstract

Highlights Varicella vaccine is a live attenuated varicella‐zoster virus. Varicella vaccine can enter latency and later reactivate as herpes zoster. Pseudorabies virus is another herpesvirus closely related to varicella‐zoster virus. The round trip model for pseudorabies virus explains pathogenesis of herpes zoster from vaccine virus.

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