Journal article
The sarcoglycan complex in limb–girdle muscular dystrophy
Current opinion in neurology, Vol.11(5), pp.443-452
10/1998
DOI: 10.1097/00019052-199810000-00006
PMID: 9847993
Abstract
The involvement of the sarcoglycan complex in the pathogenesis of muscular dystrophy is becoming increasingly clear. Sarcoglycan gene mutations lead to four forms of autosomal recessive limb-girdle muscular dystrophy. Recent progress has been made with the identification of novel mutations and their correlations with disease. Through this research, a better understanding the molecular pathogenesis of limb-girdle muscular dystrophy has been gained. Finally, animal models are now being used to study viral-mediated gene transfer for the future treatment of this disease.
Details
- Title: Subtitle
- The sarcoglycan complex in limb–girdle muscular dystrophy
- Creators
- Leland E LimKevin P Campbell
- Resource Type
- Journal article
- Publication Details
- Current opinion in neurology, Vol.11(5), pp.443-452
- DOI
- 10.1097/00019052-199810000-00006
- PMID
- 9847993
- ISSN
- 1350-7540
- eISSN
- 1473-6551
- Language
- English
- Date published
- 10/1998
- Academic Unit
- Neurology; Molecular Physiology and Biophysics; Iowa Neuroscience Institute
- Record Identifier
- 9984068265602771
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