Journal article
The search for autism disease genes
Mental retardation and developmental disabilities research reviews, Vol.10(4), pp.272-283
11/2004
DOI: 10.1002/mrdd.20041
PMID: 15666342
Abstract
Autism is a heritable disorder characterized by phenotypic and genetic complexity. This review begins by surveying current linkage, gene association, and cytogenetic studies performed with the goal of identifying autism disease susceptibility variants. Though numerous linkages and associations have been identified, they tend to diminish upon closer examination or attempted replication. The review therefore explores challenges to current methodologies presented by the complexities of autism that might underlie some of the current difficulties, and finishes by describing emerging phenotypic, statistical, and molecular investigational approaches that offer hope of overcoming those challenges. © 2004 Wiley‐Liss, Inc. MRDD Research Reviews 2004;10:272–283.
Details
- Title: Subtitle
- The search for autism disease genes
- Creators
- Thomas H WassinkLinda M BrzustowiczChristopher W BartlettPeter Szatmari
- Resource Type
- Journal article
- Publication Details
- Mental retardation and developmental disabilities research reviews, Vol.10(4), pp.272-283
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company; Hoboken
- DOI
- 10.1002/mrdd.20041
- PMID
- 15666342
- ISSN
- 1080-4013
- eISSN
- 1098-2779
- Number of pages
- 12
- Language
- English
- Date published
- 11/2004
- Academic Unit
- Psychiatry; Stead Family Department of Pediatrics
- Record Identifier
- 9984003945602771
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