The spin trapping of superoxide with M4PO (3,3,5,5-tetramethylpyrroline-N-oxide)

G. R BUETTNER; B. E BRITIGAN

doi:10.1016/0891-5849(90)90145-9

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The spin trapping of superoxide with M4PO (3,3,5,5-tetramethylpyrroline-N-oxide)

Journal article

Peer reviewed

The spin trapping of superoxide with M4PO (3,3,5,5-tetramethylpyrroline-N-oxide)

G. R BUETTNER and B. E BRITIGAN

Free radical biology & medicine, Vol.8(1), pp.57-60

1990

DOI: 10.1016/0891-5849(90)90145-9

PMID: 2157635

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Abstract

The spin trap 3,3,5,5-tetramethylpyrroline-N-oxide (M4PO) reacts with superoxide to produce a short-lived spin adduct (M4PO/.OOH, AN = 14.0 G, AH = 6.5 G) that decays by a first-order process (t1/2 approximately 35 s at pH 7.4). This short lifetime may limit its usefulness in studies of superoxide.

Fundamental and applied biological sciences. Psychology

Biological and medical sciences

Spectroscopy : techniques and spectras

Molecular biophysics

Details

Title: Subtitle: The spin trapping of superoxide with M4PO (3,3,5,5-tetramethylpyrroline-N-oxide)
Creators: G. R BUETTNER - Univ. Iowa, ESR cent., Iowa City IA 52242, United States
B. E BRITIGAN - Univ. Iowa, ESR cent., Iowa City IA 52242, United States
Resource Type: Journal article
Publication Details: Free radical biology & medicine, Vol.8(1), pp.57-60
DOI: 10.1016/0891-5849(90)90145-9
PMID: 2157635
NLM abbreviation: Free Radic Biol Med
ISSN: 0891-5849
eISSN: 1873-4596
Publisher: Elsevier Science; New York, NY
Language: English
Date published: 1990
Academic Unit: Radiation Oncology
Record Identifier: 9984046913402771

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