Journal article
The stability of diagnosis with an application to bipolar II disorder
Psychiatry research, Vol.19(4), pp.285-296
1986
DOI: 10.1016/0165-1781(86)90121-6
PMID: 3809326
Abstract
A temporal stability study (where independent diagnostic interviews are conducted at widely separated time points) is discussed and compared to a test/retest reliability study. We introduce a new battery of statistics, based on the sensitivity, specificity, and true base rate of a disorder, that qualifies either reliability or stability over time, and provide a table that relates these underlying parameters to the opening characteristics of the battery. We analyze data on 50 relatives who participated in the family study component of the National Institute of Mental Health's collaborative “Psychobiology Depression Program”. The subjects received an interview 5 years after their initial evaluation by raters without knowledge of the initial assessment. The stability of mania, hypomania, major depression, and alcoholism is considered. Although the kappa coefficient for hypomania was small (0.09), all diagnoses of hypomania in the relatives occured in the families of bipolar probands, suggesting that the low value of kappa isdue to a low sensitivity rather than to a low specificity. This is compatible with earlier findings and demonstrates the value of multiple independent assessments when studying this disorder.
Details
- Title: Subtitle
- The stability of diagnosis with an application to bipolar II disorder
- Creators
- John P Rice - John P. Rice, Ph.D., is Associate Professor of Mathematics in Psychiatry, Department of Psychiatry, and Associate Professor in the Division of Biostatistics, Department of Preventive Medicine, Washington University School of Medicine and Jewish Hospital of St. Louis, USAPatricia McDonald-Scott - Patricia McDonald-Scott, M.A., is Research Scientist, the Department of Research Assessment and Training, New York State Psychiatric Institute, USAJean Endicott - Jean Endicott, Ph.D., is Professor of Clinical Psychology, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, USAWilliam Coryell - William Coryell, M.D., is Associate Professor of Psychiatry, Department of Psychiatry, University of Iowa, USAWilliam M Grove - William M. Grove, Ph.D., is Assistant Professor of Psychiatry, Department of Psychiatry, University of Minnesota, USAMartin B Keller - Martin B. Keller, M.D., is Associate Professor of Psychiatry, Harvard Medical School, USADebby Altis - Debby Altis, B.S., is Senior Research Technician, Department of Psychiatry, Washington University School of Medicine, USA
- Resource Type
- Journal article
- Publication Details
- Psychiatry research, Vol.19(4), pp.285-296
- Publisher
- Elsevier Ireland Ltd
- DOI
- 10.1016/0165-1781(86)90121-6
- PMID
- 3809326
- ISSN
- 0165-1781
- eISSN
- 1872-7123
- Language
- English
- Date published
- 1986
- Academic Unit
- Psychiatry
- Record Identifier
- 9984003481402771
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