Journal article
The use of touch preparation for the evaluation of sentinel lymph nodes in breast cancer
The American journal of surgery, Vol.199(6), pp.792-796
2010
DOI: 10.1016/j.amjsurg.2009.06.020
PMID: 19954770
Abstract
This study was undertaken to evaluate the accuracy of touch preparation (touch prep) in the evaluation of sentinel lymph nodes (SLNs).
We performed a retrospective review of 402 breast cancer patients who underwent SLN biopsy.
A SLN was identified in 381 patients. Of 61 patients with a true positive result, 59 underwent axillary node dissection, and in 22 the SLN was the only node with metastases. Thirty-six (9.44%) had at least 1 false negative result. Twenty-five with a false negative results were due to macrometastases, with 17 (2.4%) false negatives occurring in patients with invasive ductal and 6 (5.5%) in those with invasive lobular histology,
P = .04. Touch prep had an overall sensitivity of 62.89% and specificity of 98.94%.
Touch prep for the evaluation of SLNs in breast cancer compares favorably to reported results for frozen section. False negative findings are more likely with micrometastases and invasive lobular histology.
Details
- Title: Subtitle
- The use of touch preparation for the evaluation of sentinel lymph nodes in breast cancer
- Creators
- Julie A Guidroz - Department of Surgery, University of Iowa, Iowa City, IA, USAMatthew T Johnson - Department of Surgery, University of Iowa, Iowa City, IA, USACarol E.H Scott-Conner - Department of Surgery, University of Iowa, Iowa City, IA, USABarry R De Young - Department of Pathology, University of Iowa, Iowa City, IA, USARonald J Weigel - Department of Surgery, University of Iowa, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- The American journal of surgery, Vol.199(6), pp.792-796
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.amjsurg.2009.06.020
- PMID
- 19954770
- ISSN
- 0002-9610
- eISSN
- 1879-1883
- Language
- English
- Date published
- 2010
- Academic Unit
- Molecular Physiology and Biophysics; Anatomy and Cell Biology; Surgery; Biochemistry and Molecular Biology
- Record Identifier
- 9984024411002771
Metrics
11 Record Views