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The usefulness of initial serum ferritin level as a predictor of in-hospital mortality in STEMI
Journal article   Open access   Peer reviewed

The usefulness of initial serum ferritin level as a predictor of in-hospital mortality in STEMI

Mahmoud Abdelnabi, Abdallah Almaghraby, Juthipong Benjanuwattra, Yehia Saleh, Rawan Ghazi and Ahmed Abd El Azeem
The British journal of cardiology, Vol.30(3), p.20
01/01/2023
DOI: 10.5837/bjc.2023.020
PMCID: PMC11321463
PMID: 39144088

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Abstract

Several studies have shown that elevated serum ferritin level is associated with a higher risk of coronary artery disease. Recently, it has been shown that high serum ferritin levels in men are independently correlated with an increased risk of cardiovascular mortality. This study aimed to investigate the possible correlation between the initial serum ferritin level and in-hospital mortality in patients presenting with ST-elevation myocardial infarction (STEMI). This retrospective cohort study included 890 patients who presented with acute STEMI and underwent successful primary percutaneous coronary intervention (PPCI) according to the standard techniques during the period from 1 May 2020 to 1 May 2021. At the time of admission, an initial serum ferritin level was measured in all patients. Comparison between initial ferritin levels was made between two groups: died and survived. Propensity matching was performed to exclude confounding factors effect. Forty-one patients had in-hospital mortality. There was no significant difference between both groups regarding baseline clinical characteristics. Initial serum ferritin levels were higher in deceased patients, even after propensity matching. In conclusion, even after propensity matching, initial ferritin levels were significantly higher in patients who died after being admitted for STEMI.
 Myocardial Infarction

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