Journal article
The value of touch imprint cytology in EUS-guided Trucut biopsy
Gastrointestinal endoscopy, Vol.68(1), pp.44-50
2008
DOI: 10.1016/j.gie.2007.11.042
PMID: 18355821
Abstract
Background: EUS-guided Trucut biopsy (TCB) enables the acquisition of tissue cores for histologic assessment. Touch imprint cytology (TIC) can be performed at the time of a biopsy to assess the adequacy of the sample; however, limited information is available on the diagnostic value of TIC of these specimens.
Objective: To investigate the diagnostic accuracy of TIC compared with a TCB.
Patients and design: Consecutive EUS-guided TCB and TIC (n = 109) were retrospectively and independently reviewed by a surgical pathologist (for the TCB) and a cytopathologist (for TIC) blinded to the final diagnoses.
Setting: University of Iowa Hospitals and Clinics, Iowa.
Main outcome measurements: Diagnostic accuracy of a TCB, TIC, and combined TCB + TIC.
Results: The diagnostic accuracy of a TCB was 92.7% (95% CI, 83.1%-97.3%), TIC was 82.6% (95% CI, 74.3%-88.6%), and TCB + TIC was 95.4% (95% CI, of 89.4%-98.3%). The diagnostic accuracy of a TCB alone was superior to TIC alone (P = .038); a TCB was diagnostic in 14 cases that were nondiagnostic by TIC. The addition of TIC allowed for the identification of 3 malignancies (2.8%) that were not identified on TCB alone. In 22 cases, TIC was considered diagnostic, but a TCB provided additional specific diagnostic information.
Limitations: Retrospective study and relatively low numbers.
Conclusions: TIC is a valuable tool for use in a EUS-guided TCB; TIC is independently diagnostically accurate, which allows for confidence in a rapid preliminary diagnosis, and it provides additional diagnostic value when combined with TCB.
Details
- Title: Subtitle
- The value of touch imprint cytology in EUS-guided Trucut biopsy
- Creators
- Andrew D VANDERHEYDEN - Departments of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United StatesKerry A PROCTOR - Department of Pathology Mid Columbia Medical Center, The Dalles, Oregon, United StatesMaged K RIZK - Department Internal Medicine-Gastroenterology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United StatesRogelio G SILVA - Division of Gastroenterology Advocate Christ Medical Center, Oak Lawn, Illinois, United StatesChris S JENSEN - Departments of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United StatesHenning GERKE - Department Internal Medicine-Gastroenterology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States
- Resource Type
- Journal article
- Publication Details
- Gastrointestinal endoscopy, Vol.68(1), pp.44-50
- Publisher
- Elsevier; New York, NY
- DOI
- 10.1016/j.gie.2007.11.042
- PMID
- 18355821
- ISSN
- 0016-5107
- eISSN
- 1097-6779
- Language
- English
- Date published
- 2008
- Academic Unit
- Gastroenterology and Hepatology; Pathology; Internal Medicine
- Record Identifier
- 9984047631202771
Metrics
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