Theoretical limits of spatial resolution in elliptical-centric contrast-enhanced 3D-MRA

Sean B. Fain; Stephen J. Riederer; Matt A. Bernstein; John Huston III

doi:10.1002/(SICI)1522-2594(199912)42:6<1106::AID-MRM15>3.0.CO;2-Q

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Theoretical limits of spatial resolution in elliptical-centric contrast-enhanced 3D-MRA

Journal article

Peer reviewed

Theoretical limits of spatial resolution in elliptical-centric contrast-enhanced 3D-MRA

Sean B. Fain, Stephen J. Riederer, Matt A. Bernstein and John Huston III

Magnetic resonance in medicine, Vol.42(6), pp.1106-1116

12/1999

DOI: 10.1002/(SICI)1522-2594(199912)42:6<1106::AID-MRM15>3.0.CO;2-Q

PMID: 10571932

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Abstract

The point spread function (PSF) for contrast-enhanced three-dimensional (3D) MR angiography using the elliptical centric view order is derived. This view order has been shown previously to provide high venous suppression thereby enabling long acquisition times capable of high spatial resolution. The dependence of the PSF on TR, field of view (FOV), scan time, and trigger time are shown explicitly. Theoretical predictions are corroborated with experimental results in phantoms and in vivo. The PSF width decreases as the square root of the product of TR and the two phase encoding FOV's for fixed nominal voxel size. The PSF peak amplitude increases as the reciprocal of this product. Theory and experiment demonstrate that acquisition times over 40 sec provide superior resolution compared to shorter acquisitions, despite falling levels of contrast agent concentration. The analysis predicts that an isotropic spatial resolution of 1 mm before zero filling is possible in a FOV large enough to encompass the carotid and vertebral arteries bilaterally.

contrast-enhanced MRA

elliptical centric view order

MR angiography

point spread function

Details

Title: Subtitle: Theoretical limits of spatial resolution in elliptical-centric contrast-enhanced 3D-MRA
Creators: Sean B. Fain - Mayo Clinic in Florida
Stephen J. Riederer - Mayo Clinic
Matt A. Bernstein - Mayo Clinic
John Huston III - Mayo Clinic
Resource Type: Journal article
Publication Details: Magnetic resonance in medicine, Vol.42(6), pp.1106-1116
DOI: 10.1002/(SICI)1522-2594(199912)42:6<1106::AID-MRM15>3.0.CO;2-Q
PMID: 10571932
NLM abbreviation: Magn Reson Med
ISSN: 0740-3194
eISSN: 1522-2594
Publisher: John Wiley & Sons, Inc
Number of pages: 11
Language: English
Date published: 12/1999
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Radiology; Electrical and Computer Engineering; Health, Sport, and Human Physiology
Record Identifier: 9984274954402771

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