Therapeutic trials for low back pain

Richard M Hoffman; Judith A Turner; Daniel C Cherkin; Richard A Deyo; Larry D Herron

doi:10.1097/00007632-199409151-00009

Back

Journal article

Peer reviewed

Therapeutic trials for low back pain

Richard M Hoffman, Judith A Turner, Daniel C Cherkin, Richard A Deyo and Larry D Herron

Spine (Philadelphia, Pa. 1976), Vol.19(18 Suppl), pp.2068S-2075

09/15/1994

DOI: 10.1097/00007632-199409151-00009

PMID: 7801185

View Online

Abstract

Little consensus exists regarding the indications for and effectiveness of many back pain treatments. This clinical uncertainty arises because most back pain research has been flawed by poor methodology. The authors discuss strategies for improving the quality of back pain research on treatment efficacy. Design features, including randomized treatment allocation, independent outcome assessors, comprehensive outcome measures, appropriate statistical analyses, and close patient follow-up can increase study validity. Complete descriptions of enrollment criteria, patient characteristics, and clinical interventions can increase the generalizability of results. Although large scale trials often involve university centers, community-based researchers can collaborate on randomized trials or conduct valuable cohort studies.

Outcome and Process Assessment (Health Care)

Reproducibility of Results

Follow-Up Studies

Outcome Assessment (Health Care)

Humans

Clinical Trials as Topic

Low Back Pain - therapy

Research Design

Cohort Studies

Randomized Controlled Trials as Topic

Details

Title: Subtitle: Therapeutic trials for low back pain
Creators: Richard M Hoffman - Department of Medicine, University of Washington, Seattle
Judith A Turner
Daniel C Cherkin
Richard A Deyo
Larry D Herron
Resource Type: Journal article
Publication Details: Spine (Philadelphia, Pa. 1976), Vol.19(18 Suppl), pp.2068S-2075
DOI: 10.1097/00007632-199409151-00009
PMID: 7801185
NLM abbreviation: Spine (Phila Pa 1976)
ISSN: 0362-2436
eISSN: 1528-1159
Publisher: Lippincott Williams & Wilkins
Grant note: HS-06344 / AHRQ HHS
Language: English
Date published: 09/15/1994
Academic Unit: Epidemiology; General Internal Medicine; Internal Medicine
Record Identifier: 9984094608702771

Metrics

9 Record Views