Journal article
Thermal and nutritional modulation of sleep in infant rats
Behavioral neuroscience, Vol.119(2), pp.603-611
04/2005
DOI: 10.1037/0735-7044.119.2.603
PMCID: PMC2658818
PMID: 15839806
Abstract
Infant rats cycle rapidly between periods of high muscle tone (indicative of wakefulness) and periods of atonia (indicative of sleep). Here, the influence of air temperature on sleep in 8-day-old rats was examined by testing pups at thermoneutrality (35 degrees C) and during moderate (28 degrees C) and extreme (20 degrees C) cold challenge; also, pups were tested 1, 4, and 8 hr after infusion of milk to assess the effects of food deprivation on sleep. Whereas moderate cooling slightly reduced sleep durations and altered the temporal patterning of myoclonic twitching, extreme cooling substantially decreased sleep durations and inhibited twitching. In contrast, food deprivation had little effect. Therefore, thermoregulatory mechanisms engaged during moderate cooling sustain sleep, whereas extreme cooling overwhelms these mechanisms, thereby promoting arousal.
Details
- Title: Subtitle
- Thermal and nutritional modulation of sleep in infant rats
- Creators
- Adele M H Seelke - Program in Behavioral and Cognitive Neuroscience, Department of Psychology, University of Iowa, Iowa City, IA 52242, USAMark S Blumberg
- Resource Type
- Journal article
- Publication Details
- Behavioral neuroscience, Vol.119(2), pp.603-611
- DOI
- 10.1037/0735-7044.119.2.603
- PMID
- 15839806
- PMCID
- PMC2658818
- NLM abbreviation
- Behav Neurosci
- ISSN
- 0735-7044
- eISSN
- 1939-0084
- Publisher
- United States
- Grant note
- MH50701 / NIMH NIH HHS MH66424 / NIMH NIH HHS R29 MH050701 / NIMH NIH HHS R01 MH050701-13 / NIMH NIH HHS K02 MH066424-07 / NIMH NIH HHS R01 MH050701 / NIMH NIH HHS K02 MH066424 / NIMH NIH HHS
- Language
- English
- Date published
- 04/2005
- Academic Unit
- Psychological and Brain Sciences; Iowa Neuroscience Institute; Biology
- Record Identifier
- 9984002355402771
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