Journal article
Thiosugar nucleotide analogs: Synthesis of 5′-(2,3,4-tri- O-acetyl-6- S-acetyl-6-thio-α- d-galactopyranosyl diphosphate)
Carbohydrate research, Vol.337(21), pp.1935-1940
2002
DOI: 10.1016/S0008-6215(02)00210-0
PMID: 12433459
Abstract
The synthesis of a novel analog of uridine diphosphate galactose (UDP-Gal) is described. A sulfur atom was inserted into the 6-position of galactose to give uridine 5′-(2,3,4-tri-
O-acetyl-6-
S-acetyl-6-thio-α-
d-galactopyranosyl diphosphate). This peracetylated thiol analogue of UDP-Gal has been synthesized in nine steps starting from methyl α-
d-galactopyranoside in an overall yield of 3%.
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Details
- Title: Subtitle
- Thiosugar nucleotide analogs: Synthesis of 5′-(2,3,4-tri- O-acetyl-6- S-acetyl-6-thio-α- d-galactopyranosyl diphosphate)
- Creators
- Jordan ElhalabiKevin G Rice
- Resource Type
- Journal article
- Publication Details
- Carbohydrate research, Vol.337(21), pp.1935-1940
- DOI
- 10.1016/S0008-6215(02)00210-0
- PMID
- 12433459
- NLM abbreviation
- Carbohydr Res
- ISSN
- 0008-6215
- eISSN
- 1873-426X
- Publisher
- Elsevier Ltd
- Language
- English
- Date published
- 2002
- Academic Unit
- Pharmaceutical Sciences and Experimental Therapeutics; Craniofacial Anomalies Research Center; Medicinal and Natural Products Chemistry
- Record Identifier
- 9984065697502771
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