Journal article
Three-Dimensional Geometrical Characterization of Cerebral Aneurysms
Annals of biomedical engineering, Vol.32(2), pp.264-273
02/2004
DOI: 10.1023/B:ABME.0000012746.31343.92
PMID: 15008374
Abstract
The risk of rupture of cerebral aneurysms has been correlated with the size of the aneurysm sac. It is conceivable that geometrical shape, not just size may also be related to aneurysm rupture potential. Further, aneurysm shape may also be a factor in deciding on treatment modalities, i.e., to clip or coil. However, our ability to make use of available information on aneurysm shape remains poor. In this study, methods were developed to quantify the seemingly arbitrary three-dimensional geometry of the aneurysm sac, using differential and computational geometry techniques. From computed tomography angiography (CTA) data, the three-dimensional geometry of five unruptured human cerebral aneurysms was reconstructed. Various indices (maximum diameter, neck diameter, height, aspect ratio, bottleneck factor, bulge location, volume, surface area, Gaussian and mean curvatures, isoperimetric ratio, and convexity ratio) were utilized to characterize the geometry of these aneurysm surfaces and four size-matched hypothetical control aneurysms. The physical meanings of various indices and their possible role as prognosticators for rupture risk and presurgical planning were discussed.
Details
- Title: Subtitle
- Three-Dimensional Geometrical Characterization of Cerebral Aneurysms
- Creators
- Baoshun Ma - Department of Biomedical Engineering University of Iowa Iowa City IARobert Harbaugh - Department of Neurosurgery Penn State University College of Medicine Hershey PAMadhavan Raghavan - Department of Biomedical Engineering University of Iowa Iowa City IA
- Resource Type
- Journal article
- Publication Details
- Annals of biomedical engineering, Vol.32(2), pp.264-273
- Publisher
- Kluwer Academic Publishers-Plenum Publishers; New York
- DOI
- 10.1023/B:ABME.0000012746.31343.92
- PMID
- 15008374
- ISSN
- 0090-6964
- eISSN
- 1573-9686
- Language
- English
- Date published
- 02/2004
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering
- Record Identifier
- 9984064255602771
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