Journal article
Three‐dimensional canine renovascular structure and circulation visualized in situ with the dynamic spatial reconstructor
American journal of anatomy, Vol.181(1), pp.77-88
01/1988
DOI: 10.1002/aja.1001810109
PMID: 3348149
Abstract
The dynamic spatial reconstructor–a unique, high speed, volume‐scanning, X‐ray computed tomographic imaging system–was utilized to examine canine renovascular anatomy and renal circulation in situ. In each of the four kidneys examined in this study initial scans were done during bolus injections of angiographic contrast material into the renal artery. A subsequent scan was then performed following an injection of methyl‐methacrylate‐based casting compound that had been contrast enhanced with ethiodol. After the scans, each kidney was removed, and its parenchyma was digested in potassium hydroxide to expose the vascular cast. Comparison of casts with their reconstructed images and with images obtained during injection of contrast material showed that interlobar arteries and occasionally arcuate arteries could be clearly detected. Although discrete vessels less than 1 mm in diameter could not be resolved, dynamic changes in parenchymal distribution of density during passage of contrast material allowed interpretation of flow through the multiple capillary beds of the kidney. Such analysis indicated that maximal density was in the outer‐middle zone of the cortex throughout the duration of the scan. Analysis of artery‐to‐vein transit time showed arrival of contrast material in the renal vein as soon as 3 sec, and continuation for longer than 8 sec, after the renal artery bolus. In conclusion, renal circulation in the dog can be discretely visualized with the dynamic spatial reconstructor up to the level of the arcuate arteries; however, capillary flow as a whole can be followed through the cortex, and the results suggest the presence of both rapid and slow components of peritubular circulation.
Details
- Title: Subtitle
- Three‐dimensional canine renovascular structure and circulation visualized in situ with the dynamic spatial reconstructor
- Creators
- Michael D. Bentley - Department of Physiology & Biophysics, Mayo Medical School, Rochester, Minnesota 55905.Eric A. Hoffman - Department of Physiology & Biophysics, Mayo Medical School, Rochester, Minnesota 55905.Mary J. Fiksen‐OlsenFranklyn G. Knox - Department of Physiology & Biophysics, Mayo Medical School, Rochester, Minnesota 55905.Erik L. Ritman - Department of Physiology & Biophysics, Mayo Medical School, Rochester, Minnesota 55905.J. Carlos Romero - Department of Physiology and Biophysics, Mayo Medical School, Rochester, MN 55905
- Resource Type
- Journal article
- Publication Details
- American journal of anatomy, Vol.181(1), pp.77-88
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company
- DOI
- 10.1002/aja.1001810109
- PMID
- 3348149
- ISSN
- 0002-9106
- eISSN
- 1553-0795
- Number of pages
- 12
- Language
- English
- Date published
- 01/1988
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Internal Medicine
- Record Identifier
- 9984318693502771
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