Journal article
Thyroid Nodule Molecular Testing: Is It Ready for Prime Time?
Frontiers in endocrinology (Lausanne), Vol.11, p.590128
10/09/2020
DOI: 10.3389/fendo.2020.590128
PMCID: PMC7581778
PMID: 33162941
Abstract
Cytologically indeterminate thyroid nodules remain a diagnostic and clinical challenge, and molecular testing has been advocated and advanced as a diagnostic modality to help guide treatment. While studies have expounded on the improved diagnostic certainty with these tests, data demonstrating meaningful clinical impact and supporting their routine use is still limited at best. In this review, we discuss the limitations regarding diagnostic accuracy, impact on surgical decision-making and outcomes, and cost-effectiveness of molecular testing. By highlighting the limitations of these tests, we aim to promote more thoughtful utilization of these tools in the management of thyroid nodules going forward.
Details
- Title: Subtitle
- Thyroid Nodule Molecular Testing: Is It Ready for Prime Time?
- Creators
- Tahsin M. Khan - National Institutes of HealthMartha A. Zeiger - National Institutes of Health
- Resource Type
- Journal article
- Publication Details
- Frontiers in endocrinology (Lausanne), Vol.11, p.590128
- DOI
- 10.3389/fendo.2020.590128
- PMID
- 33162941
- PMCID
- PMC7581778
- NLM abbreviation
- Front Endocrinol (Lausanne)
- ISSN
- 1664-2392
- eISSN
- 1664-2392
- Publisher
- Frontiers Media S.A
- Grant note
- National Institutes of Health
- Language
- English
- Date published
- 10/09/2020
- Academic Unit
- Surgery
- Record Identifier
- 9985224321302771
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