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Time for T
Journal article   Peer reviewed

Time for T

Jeffrey C Murray
Nature genetics, Vol.29(2), pp.107-109
10/2001
DOI: 10.1038/ng1001-107
PMID: 11586288

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Abstract

Genetic defects responsible for cleft lip and cleft palate are only now beginning to be uncovered. Mutations in the gene encoding a T-box transcription factor have been identified as the cause of the rare X-linked syndrome cleft palate with tongue-tie. And in another study, heterozygotes for a defective allele for a cell adhesion molecule, which is responsible for a rare clefting syndrome when homozygous, have been found at higher than expected incidence in sporadic forms of clefting.

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