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Tirzepatide-Induced Biphasic Anaphylactic Reaction: A Case Report
Journal article   Open access   Peer reviewed

Tirzepatide-Induced Biphasic Anaphylactic Reaction: A Case Report

Zhexiang He, Agborya N. Tabe, Sohaib Rana and Kristy King
Curēus (Palo Alto, CA), Vol.15(12), e50112
12/07/2023
DOI: 10.7759/cureus.50112
PMCID: PMC10771104
PMID: 38186543
url
https://doi.org/10.7759/cureus.50112View
Published (Version of record) Open Access

Abstract

Anaphylaxis is a rapid and severe reaction to a trigger that is characterized by skin, mucosal, and cardiorespiratory changes. A minority of patients exhibit a biphasic anaphylactic reaction (BAR). Tirzepatide is a dual incretin receptor analog approved for the treatment of type 2 diabetes mellitus (T2DM). Allergic reactions to tirzepatide were reported during clinical trials, but none were severe enough to be characterized as an anaphylactic reaction. We describe a case of a BAR to tirzepatide.
General & Internal Medicine Life Sciences & Biomedicine Medicine, General & Internal Science & Technology

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