Journal article
Total Joint Arthroplasty in Patients with Chronic Renal Disease: Is It Worth the Risk?
The Journal of arthroplasty, Vol.30(9 Suppl), pp.51-54
09/2015
DOI: 10.1016/j.arth.2014.12.037
PMID: 26122111
Abstract
26-27% of patients with end stage hip and knee arthritis requiring TJR have chronic renal disease. A multi-center, prospective clinical registry was queried for TJA's from 2006 to 2012, and 74,300 cases were analyzed. Renal impairment was quantified using estimated glomerular filtration rate (eGFR) to stratify each patient by stage of CRD (1-5). There was a significantly greater rate of overall complications in patients with moderate to severe CRD (6.1% vs. 7.6%, P<0.001). In those with CRD (Stage 3-5), mortality was twice as high (0.26% vs. 0.48%, P<0.001). Patients with Stage 4 and 5 CRD had a 213% increased risk of any complication (OR 2.13, 95% CI: 1.73-2.62). Surgeons may use these findings to discuss the risk-benefit ratio of elective TJR in patients with CRD.
Details
- Title: Subtitle
- Total Joint Arthroplasty in Patients with Chronic Renal Disease: Is It Worth the Risk?
- Creators
- Lucian C Warth - University of Iowa, Iowa City, IowaAndrew J Pugely - University of Iowa, Iowa City, IowaChristopher T Martin - University of Iowa, Iowa City, IowaYubo Gao - University of Iowa, Iowa City, IowaJohn J Callaghan - University of Iowa, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- The Journal of arthroplasty, Vol.30(9 Suppl), pp.51-54
- Publisher
- United States
- DOI
- 10.1016/j.arth.2014.12.037
- PMID
- 26122111
- ISSN
- 0883-5403
- eISSN
- 1532-8406
- Language
- English
- Date published
- 09/2015
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Orthopedics and Rehabilitation; Internal Medicine
- Record Identifier
- 9984040220502771
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