Journal article
Total Synthesis of the Highly Potent Anti-HIV Natural Product Daurichromenic Acid along with Its Two Chromane Derivatives, Rhododaurichromanic Acids A and B
Organic letters, Vol.5(23), pp.4481-4484
11/01/2003
DOI: 10.1021/ol030109m
PMID: 14602030
Abstract
(Equation presented) The highly potent anti-HIV natural product daurichromenic acid was successfully synthesized in only five steps with 49% overall yield. The key step in the synthetic strategy involves a microwave-assisted tandem condensation and intramolecular SN2′- type cyclization to form the 2H-benzopyran core structure.
Details
- Title: Subtitle
- Total Synthesis of the Highly Potent Anti-HIV Natural Product Daurichromenic Acid along with Its Two Chromane Derivatives, Rhododaurichromanic Acids A and B
- Creators
- Ying Kang - University of IowaYan Mei - University of IowaYuguo Du - University of IowaZhendong Jin - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Organic letters, Vol.5(23), pp.4481-4484
- DOI
- 10.1021/ol030109m
- PMID
- 14602030
- ISSN
- 1523-7060
- eISSN
- 1523-7052
- Language
- English
- Date published
- 11/01/2003
- Academic Unit
- Pharmaceutical Sciences and Experimental Therapeutics; Medicinal and Natural Products Chemistry
- Record Identifier
- 9984365890202771
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