Journal article
Total synthesis of pawhuskin C: a directed ortho metalation approach
Tetrahedron letters, Vol.46(8), pp.1321-1324
2005
DOI: 10.1016/j.tetlet.2004.12.114
Abstract
[Display omitted] The total synthesis of the opioid modulator pawhuskin C has been accomplished in eight steps from methyl 3,5-dihydroxybenzoate. The key step in this sequence is a directed ortho metalation reaction conducted without protection of a benzylic alcohol and thus presumed to involve a formal dianion intermediate.
Details
- Title: Subtitle
- Total synthesis of pawhuskin C: a directed ortho metalation approach
- Creators
- Jeffrey D NeighborsMaya S SalnikovaDavid F Wiemer
- Resource Type
- Journal article
- Publication Details
- Tetrahedron letters, Vol.46(8), pp.1321-1324
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.tetlet.2004.12.114
- ISSN
- 0040-4039
- eISSN
- 1873-3581
- Language
- English
- Date published
- 2005
- Academic Unit
- Chemistry; Neuroscience and Pharmacology
- Record Identifier
- 9983985918602771
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