Journal article
Tracheomegaly: a complication of fetal endoscopic tracheal occlusion in the treatment of congenital diaphragmatic hernia
Pediatric radiology, Vol.40(5), pp.674-680
05/01/2010
DOI: 10.1007/s00247-009-1437-9
PMID: 19894042
Abstract
Fetal endoscopic tracheal occlusion (FETO) is a promising treatment for severe congenital diaphragmatic hernia, a condition that carries significant morbidity and mortality. It is hypothesised that balloon occlusion of the fetal trachea leads to an improvement in lung growth and development. The major documented complications of FETO to date are related to preterm delivery.
To report a series of five infants who developed tracheomegaly following FETO.
Review of all children referred with tracheomegaly to the paediatric intensive care and tracheal service at two referral centres.
Five neonates presented with features of respiratory distress shortly after birth and were subsequently found to have marked tracheomegaly. Two neonates had tracheomalacia in addition.
There are no previous reports in the literature describing tracheomalacia, or more specifically, tracheomegaly, as a consequence of FETO. We propose that the particularly compliant fetal airway is at risk of mechanical damage from in utero balloon occlusion. This observation of a new problem in this cohort suggests a thorough evaluation of the trachea should be performed in children who have had FETO in utero. It may be that balloon occlusion of the trachea earlier in utero (before 26 weeks' gestation) predisposes to this condition.
Details
- Title: Subtitle
- Tracheomegaly: a complication of fetal endoscopic tracheal occlusion in the treatment of congenital diaphragmatic hernia
- Creators
- Kieran McHugh - Great Ormond Street HospitalAsim Afaq - Great Ormond Street HospitalNigel Broderick - Nottingham University Hospitals NHS TrustHany O. Gabra - Great Ormond Street HospitalDerek J. Roebuck - Great Ormond Street HospitalMartin J. Elliott - Great Ormond Street Hospital
- Resource Type
- Journal article
- Publication Details
- Pediatric radiology, Vol.40(5), pp.674-680
- DOI
- 10.1007/s00247-009-1437-9
- PMID
- 19894042
- NLM abbreviation
- Pediatr Radiol
- ISSN
- 0301-0449
- eISSN
- 1432-1998
- Publisher
- Springer Nature
- Number of pages
- 7
- Language
- English
- Date published
- 05/01/2010
- Academic Unit
- Radiology
- Record Identifier
- 9984318811202771
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