Journal article
Trachyspermum ammi 10 % topical cream versus placebo on neuropathic pain, a randomized, double-blind, placebo-controlled trial
Neurological sciences, Vol.37(9), pp.1449-1455
09/01/2016
DOI: 10.1007/s10072-016-2600-3
PMID: 27166709
Abstract
A four-week, double-blind, randomized, placebo-controlled trial was conducted to assay the effectiveness of Ajwain 10 % (Trachyspermum ammi Sprague) topical cream on neuropathic pain. Intervention encompassed Ajwain 10 % and placebo creams. Ninety-two patients who specifically mentioned daily and nocturnal burning feet were randomly assigned to receive one of those interventions. Presence and decline in patients' numbness, tingling and allodynia were also evaluated. Major outcome measure was alteration in feet burning intensity (final week versus baseline week) regarding to a visual analog scale on a 0-10 cm scale (0 being "no pain", 10 being "worst pain"). Significant reduction in feet burning scores as well as numbness, tingling and allodynia were found in Ajwain group compared to placebo. This trial examining a cream of Ajwain essential oil versus placebo revealed the significance difference between two groups. This medicament can be a good candidate for the alleviation of feet burning, a neuropathic complication.
Details
- Title: Subtitle
- Trachyspermum ammi 10 % topical cream versus placebo on neuropathic pain, a randomized, double-blind, placebo-controlled trial
- Creators
- Peyman Petramfar - Shiraz University of Medical SciencesMahmoodreza Moein - Shiraz University of Medical SciencesSoliman Mohammadi Samani - Shiraz University of Medical SciencesSayed Hamidreza Tabatabaei - Shiraz University of Medical SciencesMohammad M Zarshenas - Shiraz University of Medical Sciences
- Resource Type
- Journal article
- Publication Details
- Neurological sciences, Vol.37(9), pp.1449-1455
- DOI
- 10.1007/s10072-016-2600-3
- PMID
- 27166709
- NLM abbreviation
- Neurol Sci
- ISSN
- 1590-1874
- eISSN
- 1590-3478
- Language
- English
- Date published
- 09/01/2016
- Academic Unit
- Neurology
- Record Identifier
- 9985014709402771
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