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Transection of subfornical organ neural connections diminishes the pressor response to intravenously infused angiotensin II
Journal article   Peer reviewed

Transection of subfornical organ neural connections diminishes the pressor response to intravenously infused angiotensin II

R. Wallace Lind, Lynne E Ohman, Mary B Lansing and Alan Kim Johnson
Brain research, Vol.275(2), pp.361-364
1983
DOI: 10.1016/0006-8993(83)90998-8
PMID: 6626986

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Abstract

Knife-cut lesions were used to assess the participation of the subfornical organ (SFO) in the central pressor action of intravenously administered angiotensin. Knife-cuts of the ventral stalk of the SFO significantly attenuated pressor responses during infusion of 3 doses of angiotensin, although responses to bolus injections were unaffected. These results are consistent with previous work in implicating the SFO as an important mediator of the central pressor action of circulating angiotensin.
angiotensin blood pressure drinking rat subfornical organ

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