Journal article
Transgenic models as tools for studying the regulation of human renin expression
Regulatory Peptides, Vol.86(1), pp.77-82
2000
DOI: 10.1016/S0167-0115(99)00097-X
PMID: 10672905
Abstract
Transgenic mice and rats have become popular tools to study the regulation of gene expression and the consequences of protein over-production. Over the past decade, numerous transgenic models have been developed to study the mechanisms of human renin gene expression and the participation of the renin–angiotensin system in the development of hypertension. Herein we will provide an overview of what has been learned from the use of transgenic models for studying the human renin gene.
Details
- Title: Subtitle
- Transgenic models as tools for studying the regulation of human renin expression
- Creators
- Patrick L. Sinn - University of IowaCurt D. Sigmund - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Regulatory Peptides, Vol.86(1), pp.77-82
- Publisher
- Elsevier B.V
- DOI
- 10.1016/S0167-0115(99)00097-X
- PMID
- 10672905
- ISSN
- 0167-0115
- eISSN
- 1873-1686
- Language
- English
- Date published
- 2000
- Academic Unit
- Molecular Physiology and Biophysics; Microbiology and Immunology; Pulmonary Medicine; Stead Family Department of Pediatrics; Neuroscience and Pharmacology
- Record Identifier
- 9984297315702771
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