Journal article
Translational research in endocrine surgery
Surgical oncology clinics of North America, Vol.22(4), pp.857-884
10/2013
DOI: 10.1016/j.soc.2013.06.012
PMCID: PMC3794713
PMID: 24012403
Abstract
This article reviews translational research in endocrine surgery, with a focus on disorders of the thyroid, parathyroids, adrenals, and endocrine pancreas. Discovery of genes responsible for heritable endocrine cancer syndromes has increased knowledge of the causes and mechanisms of endocrine cancer and has refined surgical treatment options. Knowledge of mutations in sporadic cancer has led to rapid progress in small-molecule kinase inhibitor strategies. These breakthroughs and their influence on current therapy are discussed to provide surgeons with an overview of the basic science research currently creating new clinical treatments and improving patient care.
Details
- Title: Subtitle
- Translational research in endocrine surgery
- Creators
- Scott K Sherman - Department of Surgery, Carver College of Medicine, The University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USAJames R Howe
- Resource Type
- Journal article
- Publication Details
- Surgical oncology clinics of North America, Vol.22(4), pp.857-884
- DOI
- 10.1016/j.soc.2013.06.012
- PMID
- 24012403
- PMCID
- PMC3794713
- NLM abbreviation
- Surg Oncol Clin N Am
- ISSN
- 1055-3207
- eISSN
- 1558-5042
- Publisher
- United States
- Grant note
- 5T32 CA148062-03 / NCI NIH HHS T32 CA148062 / NCI NIH HHS
- Language
- English
- Date published
- 10/2013
- Academic Unit
- Surgery
- Record Identifier
- 9984051767902771
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