Journal article
Traumatic Brain Injury in Children and Adolescents: Psychiatric Disorders 24 Years Later
The journal of neuropsychiatry and clinical neurosciences, Vol.34(1), pp.60-67
01/01/2022
DOI: 10.1176/appi.neuropsych.20050104
PMCID: PMC9818773
PMID: 34538075
Abstract
The investigators aimed to extend findings regarding predictive factors of psychiatric outcomes among children and adolescents with traumatic brain injury (TBI) from 2 to 24 years postinjury.
Youths aged 6-14 years who were hospitalized following TBI from 1992 to 1994 were assessed at baseline for TBI severity and for preinjury psychiatric, adaptive, and behavioral functioning; family functioning; family psychiatric history; socioeconomic status; and intelligence within weeks of injury. Predictors of psychiatric outcomes following pediatric TBI at 3, 6, 12, and 24 months postinjury have previously been reported. In this study, repeat psychiatric assessments were completed at 24 years postinjury with the same cohort, now adults aged 29-39 years, with the outcome measure being presence of a psychiatric disorder not present before the TBI ("novel psychiatric disorder").
Fifty participants with pediatric TBI were initially enrolled, and the long-term outcome analyses focused on data from 45 individuals. Novel psychiatric disorder was present in 24 out of 45 (53%) participants. Presence of a current novel psychiatric disorder was independently predicted by the presence of a preinjury lifetime psychiatric disorder and by severity of TBI.
Long-term psychiatric outcome (mean=23.92 years [SD=2.17]) in children and adolescents hospitalized for TBI can be predicted at the point of the initial hospitalization encounter by the presence of a preinjury psychiatric disorder and by greater injury severity.
Details
- Title: Subtitle
- Traumatic Brain Injury in Children and Adolescents: Psychiatric Disorders 24 Years Later
- Creators
- Jeffrey E Max - University of California San DiegoEmily A Troyer - University of California San DiegoHattan Arif - University of California San DiegoFlorin Vaida - University of California San DiegoElisabeth A Wilde - University of California San DiegoErin D Bigler - University of California San DiegoJohn R Hesselink - University of California San DiegoTony T Yang - University of California San DiegoOlga Tymofiyeva - University of California San DiegoOwen Wade - University of California San DiegoJane S Paulsen - University of California San Diego
- Resource Type
- Journal article
- Publication Details
- The journal of neuropsychiatry and clinical neurosciences, Vol.34(1), pp.60-67
- DOI
- 10.1176/appi.neuropsych.20050104
- PMID
- 34538075
- PMCID
- PMC9818773
- NLM abbreviation
- J Neuropsychiatry Clin Neurosci
- ISSN
- 0895-0172
- eISSN
- 1545-7222
- Grant note
- T32 MH018399 / NIMH NIH HHS U01 NS103475 / NINDS NIH HHS U01 NS105509 / NINDS NIH HHS R01 NS103475 / NINDS NIH HHS R21 AT009173 / NCCIH NIH HHS U01 NS082089 / NINDS NIH HHS R01 HD088438 / NICHD NIH HHS UL1 TR001872 / NCATS NIH HHS R01 NS105509 / NINDS NIH HHS R61 AT009864 / NCCIH NIH HHS
- Language
- English
- Date published
- 01/01/2022
- Academic Unit
- Psychiatry; Psychological and Brain Sciences
- Record Identifier
- 9984383913502771
Metrics
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